الفهرس 
Vas DeferensOnly 14 pages are availabe for public view
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Abstract
C-kit positive cells outside the gastrointestinal tract
(GIT) which are morphologically similar to interstitial cells of cajal (ICC)
in the GIT were supposed to play same role of motility in organs other
than the GIT. Aim of the work: To observe the effect of ischemia
reperfusion injury I/R injury on the rat vas deferens with reference to
interstitial cajal like cells (ICLC). Materials and Methods: This study
was performed on 35 male albino rats weighing 180-200 gm divided into
3 main groups; control group (A), ischemia group (B) and reperfusion
group (C) after applying spermatic cord torsion for one hour followed by
detorsion. All sections from the different groups were stained with
heamatoxylin and eosin (H & E), toludine blue and c-kit
immunohistochemichal staining and morphometric study was done
recording the mean area percent of c-kit positive (ICLC). Results: The
examined H & E sections showed histological changes in ischemia group
and the first two subgroups of reperfusion C1, C2 and relative recovery in
the other two subgroups C3, C4. The mean area percentage of c-kit
positive ICLC in the ischemia group and the first two subgroups C1, C2
of reperfusion was significantly decreased compared to the control. The
other two subgroups C3, C4 of the reperfusion group showed relatively
increasing of the mean area percentage of the c-kit positive ICLC
compared to the control. Conclusions: it was concluded that I/R injury
had evident histopathologicl effects on the vas deferens that affected also
its ICLC. This changes might explain abnormal vas deferens motility in
I/R injury and might explain some of infertility causes.