الفهرس 
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Abstract
Acinetobacters play a significant role in the colonization and infection of patients admitted to hospitals, They have been immplicated in a varity of nosocomial infections including bacteremia, pneumonia,UTI and meningitis.Such infections are offften extremely difficult to treat because of widespread resistance of these bacteria to the major groups of antibiotics. Various mechanisms of antibiotic resistance have been recognized in these bacteria and combination therpy is usually required for effective treatment. This study was conducted in Suez Canal Univeristy Hospital to explore different prevalent biotypes, detect their resistance pattern, to examine synergistic effect of different antibiotic combination and to determine mechanism of resistance. During the period of study extending from june2011 to february 2012,350 clinical specimens were collected from 350 nosocomially infected patients from different ICU wards of the hospital including general ICU, hepatology ICU, NICU,BICU and CCU.ALL age groups and both sexes were included in the study. All respiratory. urine, burn wound and blood specimens were cultured onto different medias according to type of specimen.