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العنوان
The protective role of vitamin E and L-carnitine against the atherosclerotic effect of triton WR 1339 in male rats /
المؤلف
Abu Zaid, Muhammad Muhammad Fekry Muhammad.
هيئة الاعداد
باحث / محمد محمد فكرى محمد أبو زيد
مشرف / ابراهيم كامل الشوربجى
مناقش / ابراهيم فتوح حسن
مناقش / صلاح احمد شويتة
الموضوع
Chemistry.
تاريخ النشر
2012.
عدد الصفحات
p 157. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Physical and Theoretical Chemistry
تاريخ الإجازة
20/11/2012
مكان الإجازة
جامعة طنطا - كلية العلوم * - الكيمياء الحيوية
الفهرس
Only 14 pages are availabe for public view

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Abstract

Tyloxapol (Triton WR 1339) is a non-ionic detergent that inhibits lipoprotein lipase and thereby raises levels of serum lipids. The present study investigated the protective effects of vitamin E, L- carnitine and their combination against the hyperlipidemic effect of triton WR 1339 in heart and liver tissues of male rats. A total of 104 male albino rats were divided randomly into eight groups (13 rats, 3 rats were excluded from each group for the histopathological examinations). The control group was received saline, the triton group was injected by triton WR 1339 via the tail (50 mg/lOOg BW), the L-camitine group was injected intraperitoneally with L-camitine only(600 mg/kg BW), the triton-L-carnitine group was injected with triton plus L-carnitine, the vitamin E group was treated orally with vitamin E only (0.54 g/Kg BW), the triton-vitamin E group was injected with triton plus vitamin E, the combination group was treated with L-carnitine plus vitamin E and the triton-combination group was injected by triton plus the combination.