الفهرس 
Introduction and aim of the worrkOnly 14 pages are availabe for public view
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Abstract
Wide spread of antimicrobials without previous sensitivity testing especially in the field of poultryproductionresulted in the development of multi drug resistant isolates. An emerging option to fight such pathogens is the combination therapy. This work was planned as an attempt to explore the pattern of some antimicrobials resistance and to thraw spot lights on some antimicrobials interactions and the antibacterial activity against some gram-positive bacterial isolates to give an ideas for practitioners to draw their strategy for treatment of infectious disease. For attaining this goal: A total of 90chickens specimens from visceral organ, (liver, spleen, heart,kidney) and swabs from suspected lesion of chicken (pus swabs from pumble foot, nasal swabs from chicken nares) were collected from different localities in EI-Dakahlia Governorate. The bacteriological and biochemical identification revealed 20 gram- positive isolates (14 isolates were s’aureus, 2 isolates were coagulase- negative staphylococci and 4 isolates were enterococci ).
The in vitro antimicrobial sensitivity pattern of these isolates was done and the intermediate seneitive isolates were checked for both qualitative and quantitative methods for different antibiotic combinations and the obtained data revealed, that there were synergistic interactions between gentamicin and cefotaxime with FIC 0.5 , between gentamicin and amoxicillin with FIC 0.5 and between cefotaxime and amoxicillin with FIe 0.5 for enterococci strain by both qualitative and quantitative methods. For coagulase negative staphylococci, synergistic interactions were reported by qualitative and quantitative methods between rifampicin