الفهرس 
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Abstract
Fascioliasis is the disease caused by liver fluke. Sheep and cattle are the
most commonly affected, also other farm animals, horses, deer, goats also may
be infected by liver fluke; humans are also occasionally infected. The present
study was devoted to throw light on impact of fascioliasis among farm animals
and man in some endemic foci in Egypt.
To achieve this goal, coprological and serological techniques were
carried out, as well as to compare between the excretory/ secretory (EIS) and
crude antigens in serological diagnosis of fascioliasis by using ELISA.
Coprological examination was carried out on 245 fecal samples
collected from 78 sheep, 116 cattle and 51 buffaloes for detection of Fasciola
egg. Moreover, 5556 stool samples taken from human also for detection of
fasciola egg were collected from patients suffering from liver disorder in Giza
and Cairo governorates.
Serological examination was carried out on serum samples prepared
from blood samples obtained from the same coprologically tested farm animals
collected from Cairo and Giza abattoirs. CoprologicaI examination concomitant
with serological examination on (46) patients in Cairo and Giza.
The obtained results indicated that the serological examination is more
sensitive than coprological examination, and can detect early infection of
fascioliasis, moreover, the EIS antigen is more antigenic and specific than the
crude antigen by using ELISA.