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Abstract The aim of this study was to evaluate the risk of untreated ISH in elderly and to correlate this risk with clinical measurement versus ambulatory blood pressure monitoring. Conclusion and recommendation: It can be concluded that ISH is not a benign condition or normal sequence of aging but it is a disease that has a worse outcome on target organ damage the ambulatory blood pressure monitoring is superior to clinic B.P in diagnosis and prediction of target organ damage among those patients. Based on the data received from this study we recommend: 1- Use of ambulatory blood pressure monitoring in diagnosis of ISH incidence of WCH is high among those patients. 2- Frequent assessment of target damage in those patients by echocardiography, microalbuminuria, fundus examination and study of retroocular blood flow. 3- Prompt treatment of ISH by non-pharmacological and pharmacological tools that might stop or reverse target organ damage with ISH. 4- Further study is needed to establish the relationship between the retroocular blood velocity and the retinal and choroidal blood flow as well as the structure of retinal and choroidal blood vessel using fluorescen angiography, a study might give a clue to the pathogenesis of retinopathy in such cases. |