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العنوان
Relation of High Density Lipoprotein Cholesterol, Apolipoproteins B & A-1 to the Presence, Ectent and Severity of Angiographically Documented Atherosclerotic Coronary Artery Disease
الناشر
Adel Hamdy Mahmoud ,
المؤلف
Mahmoud, Adel Hamdy
هيئة الاعداد
باحث / Adel Hamdy Mahmoud
مشرف / Helmy Ahmed Shalby
مشرف / Ali Mohamed Hegazy
مشرف / Sanaa Abd EL-Shafy
الموضوع
Cardiology Serum Lipoproteins Dyslipoproteinemia Dyslipoproteinemia and Atheresclerosis
تاريخ النشر
1995 .
عدد الصفحات
160 p.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
1/1/1995
مكان الإجازة
جامعة المنيا - كلية الطب - Cardiology
الفهرس
Only 14 pages are availabe for public view

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Abstract

Aim of the work
To determine the relation of lipid, lipoproteins (HDL-C & LDL-C) and Apo lipoproteins (Apo-B & Apo A-1) to the presence, the extent and the degree of severity of CAD.
Conclusion
The present study indicated inverse relation of HDL-C with extent and severity of CAD in the patients with low total serum cholesterol.
The total cholesterol/ HDL-C ratio constitutes a more convenient & efficient profile because it reflects the joint effect of the 2-way traffic of cholesterol entering and leaving the tissues.
The serum level of Apo A-1 is a better marker for the presence of CAD than HDL-C and a normal Apo A-1 can provide an argument against pharmacological therapy inspite of decreased level of HDL-C.
The serum level of Apo B is a better marker for the presence, extent and severity of CAD.
The patients with elevated serum level of Apo B inspite of normal LDL-C level are candidate for drug therapy.
So, it is concluded that assessment of serum level of HDL-C, Apo A-1 and Apo B become very essential in the risk stratification and management of dyslipidemia and atherosclerosis.