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Abstract the Ambulator) anesthesia has become recognized as 41 anesthetic subspecialty, expansion of this specialty is likely to continue with the growth in minimally-invasive surgical procedures. The ability to control postoperative pain may make the difference between performing a given procedure on an inpatient or ambulatory basis. Tramadol, an analgesic deriving part of its effect via opioid ■ Agonist activity, might provide postoperative pain relief with minimal I risk of respiratory depression. Meperidine is an upload agonist. binds to (.i-and ic-opioid receptors and is commonly used in treatment of postoperative pain. ■ Nalbuphine is an upload kappa-agonist, mu-anatomist. 0L) limes as potent as morphine It has several advantages over other commonly used narcotic analgesics, little effect on the cardiovascular system and a lower incidence of nausea and vomiting. This stud) was earned out on 60- ASA I or II patients scheduled for elective surgery m Alexandria University Hospital ■ The aim of this work was to compare the recovery pattern and : The analgesic effects of intravenous tramadol, meperidine or ; nalbuphine and to determine the propensity of tramadol and ■ nalbuphine to induce respirator) depression relative to meperidine in I doses commonl) used in clinical practice |