الفهرس 
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Abstract
The present work studied the adverse effects of a local isolate of
haemorrhagic enteritis virus (HEV I) and preparation of a vaccine from the
local isolate and evaluation of its potency as compared with an imported,
commercially available live vaccine.
In one experiment, the adverse effects of HEV 1 were studied by
determination of the heterophil function, total leucocytic count (TLC),
differential leucocytic count (DLC), total serum proteins, body weight gain,
spleen index and immune response to Newcastle disease (ND) and fowl
pox live virus vaccines in 8 groups of 52 days old turkey poults. Results
achieved are summarized in the following: 1- Measurement of the heterophil percentage and phagocytic activity in heparinized blood stimulated with latex and unstimulated from 52 days old turkey poults infected orally with 103 median turkey infective dose (TIDso) of HEV1 revealed significantly lower values (P<0.05) at 3, 7 and 14 days post infection (P.1) than in respective uninfected groups.
Differences in both values between infected and uninfected groups were
insignificant by day 21 P.I.
2- The differential leucocytic count showed significant lymphyopenia on
day 3 and 7 P.1 in groups infected with HEV I. Heterophil percent in all
groups ofpoults infected with HEV1 was higher on day 3 and 7 P.1 than
uninfected groups. Esenophils, basophils, and monocytes percent were
not significantly changed in both HEVI-infected and uninfected poults.
3- The serum total protein levels were significantly lower at the 3rd, ih and
14th day P.1 only in groups infected with HEV1 than in uninfected